[ensembl-dev] VEP dbNSFP Plugin

Irina Armean iarmean at ebi.ac.uk
Mon Aug 24 17:40:34 BST 2020


Hi Sage,

If you want to use the GRCh37 REST server version, then dbNSFPv4.0a.zip 
is the one. You can use this version of zip as long as you process it 
according to the plugin instructions for GRCh37.

The dbNSFPv3.5a can also be found on dbNSFP's google drive. Hope that 
link works for you: https://sites.google.com/site/jpopgen/dbNSFP .
<https://sites.google.com/site/jpopgen/dbNSFP>

Kind regards,

Irina


On 21/08/2020 19:56, Sage Hornung wrote:
>
> Hi,
>
> The instructions in the vep plugin page for the dbNSFP  plugin say to 
> use the dbNSFPv3.5a.zip for GRCh37/hg19 but it’s no longer available 
> at ftp://dbnsfp:dbnsfp@dbnsfp.softgenetics.com 
> <ftp://dbnsfp:dbnsfp@dbnsfp.softgenetics.com>
>
> Any suggestions as to what I can use for GRCh37? Can I use the 
> dbNSFPv4.0a.zip. (I did find the 3.5a version elsewhere)
>
> I would like to use the same version found here 
> https://grch37.rest.ensembl.org/ <https://grch37.rest.ensembl.org/>
>
> Thank You,
>
> Sage
>
> *Sage Hornung*
>
> /Software Engineer /
>
> *NeoGenomics Laboratories, Inc.*
>
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-- 
Irina Armean PhD, Bioinformatican
Ensembl Variation, EMBL-EBI, Hinxton, UK

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