[ensembl-dev] Most severe annotation per allele

Will McLaren wm2 at ebi.ac.uk
Tue Jun 3 09:32:23 BST 2014


Hi Konrad,

There isn't currently, but this is something that could be added in future.

Regards

Will McLaren
Ensembl Variation


On 2 June 2014 20:55, Konrad Karczewski <konradk at broadinstitute.org> wrote:

> Hello!
>
> I've noticed all the collapsing options (--pick, --most_severe, and
> --per_gene) all seem to choose one consequence per VCF record. However, I
> would think that for multi-allelic sites, it may be advantageous in many
> cases to return one for each alternate allele. Maybe I missed it, but is
> there a way to do this in VEP?
>
> Thanks!
> -Konrad
>
>
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