[ensembl-dev] Conservation_score = GERP?

guillermo.marco at sistemasgenomicos.com guillermo.marco at sistemasgenomicos.com
Wed May 29 11:25:15 BST 2013


I'm missing GERP p-value but I can't find it inside
http://www.ensembl.org/info/docs/Doxygen/compara-api/classBio_1_1EnsEMBL_1_1Compara_1_1ConservationScore.html

It's ok. I'll take a look further.

Thanks.

Best regards,
Guillermo.

> Hi Guillermo,
>
> I'm not exactly sure what question you are asking; the Conservation.pm
> plugin by default fetches GERP conservation scores, but the plugin's
> configuration allows you to specify a different method e.g.:
>
> --plugin Conservation,[alt_method]
>
> I'm not familiar with this area of the API - you should consult the
> Compara
> documentation:
>
> http://www.ensembl.org/info/docs/compara/index.html
>
> Regards
>
> Will
>
>
> On 28 May 2013 17:04, Guillermo Marco Puche <
> guillermo.marco at sistemasgenomicos.com> wrote:
>
>>  Hello,
>>
>> I'm using Conservation score plugin from VEP repository. But I've a
>> doubt
>> since long time ago I used GERP method (which I believe is now
>> deprecated).
>>
>> I'm confused, so now Conservation score equals GERP? (*Genomic
>> Evolutionary Rate Profiling* score is the estimation of the conservation
>> for a position in the evolutionary scale through multiple alignments)
>>
>> Thank you :)
>>
>> Best regards,
>> Guillermo.
>>
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