[ensembl-dev] Polyphen scores
Graham Ritchie
grsr at ebi.ac.uk
Tue Aug 16 11:12:25 BST 2011
Hi Chris,
It is indeed the value from the pph2_prob column, extracted after we have run the weka classifier.
Cheers,
Graham
On 16 Aug 2011, at 11:06, cj5 at sanger.ac.uk wrote:
> Hi ,
> Just wanted to what is provided by TranscriptVariationAllele::polyphen_score
>
> Is this the pph2_prob 'classifier probability of the variation being
> damaging', as described here ?:
> http://genetics.bwh.harvard.edu/pph2/dokuwiki/appendix_a
>
> Many Thanks
>
> --
> Chris Joyce
> Team 136, Medical Sequencing
> Wellcome Trust Sanger Institute
> Tel: 01223 834244 Ext. 6859
>
>
>
>
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