[ensembl-dev] REVEL Pluging in VEP 110

[Diana Lemos]

Hi,

The plugin was updated after release 108 which could have caused 
differences in the output.

Can you please send an example of your input file with variants that 
were expected to have a REVEL score but didn't with version 110?

Also, when did you download the REVEL file?




On 08/12/2023 08:15, Souhila Amanzougarene wrote:
> Dear Ensembl Team,
>
> I'm using VEP tool version 110 to annotate a VCF file (hg38) with the 
> REVEL plugin. I processed it by running the following command :
>
> ./vep -i variations.vcf --assembly GRCh38 --plugin 
> REVEL,file=/path/to/revel/data.tsv.gz
>
> This command runs without any errors, but the REVEL column is empty in 
> the annotated VCF.
>
> I attempted to run VEP 110 using the REVEL.pm file from VEP 108, and 
> it worked, I now have scores in the REVEL column.
>
>
> Thak you for your assisatnce !
>
> Best regards,
>