[ensembl-dev] Error 503 GRCh37

Kirill Tsukanov ktsukanov at ebi.ac.uk
Tue Oct 6 14:52:01 BST 2020


Hi Johann,

To add to what Dan said, here's an example of the implementation of the 
backoff-then-retry loop which he mentioned in our Python package: [1]. 
Perhaps this could be useful.

[1] 
https://github.com/EBIvariation/eva-opentargets/blob/7bca316956066f8a79b6c7e931c62efec91be2d2/vep-mapping-pipeline/vep_mapping_pipeline/consequence_mapping.py#L54

Best wishes, Kirill
Kirill Tsukanov | Senior Bioinformatician
European Variation Archive, EMBL-EBI

On 05/10/2020 18:56, Dan Sheppard wrote:
> Hi Johann,
>
> Thanks for your message. We've noticed a higher than normal error rate
> both on GRCh37 REST, and also on certain main REST endpoints; it has
> set off a number of monitoring alarms. We have been looking into the
> errors and these seem to be caused by recent increases in data volume,
> meaning that we need to re-tweak some resource settings to maintain
> adequate throughput. We should have this completed within the next few days,
> and hopefully error rates will reduce.
>
> There is no reason to believe that your script is misusing the service
> on the basis of this outcome, but thank you for your concern. It's always
> a good idea to wrap calls in some kind of backoff-then-retry loop but I
> understand how frustrating it can be if things seem to constantly stall.
>
> I will keep you posted.
>
> Dan.
>
> On Mon, Oct 05, 2020 at 03:03:50PM +0200, Johann Lieberwirth wrote:
>> Dear Ensembl Developers,
>>   
>> I’m using VEP REST services for annotations with the python package requests and am receiving a lot of ERROR 503 for about one week now. They occur only for GRCh37 as far as I noticed. If I refresh the request for a couple of times without changing any parameters, at some point I get the expected results. This is a little unreliable. Is this a misuse of the service from my side or is there some problem on yours?
>>   
>> Best,
>> Johann
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