[ensembl-dev] LD : Number of genotypes supported by the program (250) exceeded
Catherine Leroy
cleroy at ebi.ac.uk
Mon Feb 23 12:56:02 GMT 2015
Thank you very much! :-)
On 23 Feb 2015, at 11:13, Will McLaren <wm2 at ebi.ac.uk> wrote:
> Hi Catherine,
>
> Yes, you can increase the number by editing and recompiling the C code used to calculate the LD values:
>
> (/path/to/src/ is where you have the ensembl-variation API module).
>
> cd /path/to/src/ensembl-variation/C_code
> sed -i.bak "s/#define SIZE 250/#define SIZE 500/" calc_genotypes.c
> make
>
> You then have to either copy the resultant calc_genotypes file somewhere in your path, or add the path to your PATH environment variable
>
> export PATH=/path/to/src/ensembl-variation/C_code:${PATH}
>
> if you use BASH, or
>
> setenv PATH /path/to/src/ensembl-variation/C_code:${PATH}
>
> if you use tcsh or csh.
>
> If you re-run your script it should then use the recompiled binary.
>
> HTH
>
> Will McLaren
> Ensembl Variation
>
> On 23 February 2015 at 10:15, Catherine Leroy <cleroy at ebi.ac.uk> wrote:
> Hello,
>
> Me again! Again on LD.
>
> I’m still trying to get for :
> snp : rs11010067
> all the LD r2 values.
>
> If I use population : 1000GENOMES:phase_1_EUR
> I get the following message :
> Number of genotypes supported by the program (250) exceeded
>
> I can work around that using population :
> 1000GENOMES:phase_1_GBR
> which is a sub population of 1000GENOMES:phase_1_EUR.
>
> Is there any way I can increase the 250 limit to be able to use 1000GENOMES:phase_1_EUR? As this would be probably more representative then the sub population?
>
> Thanks for your help,
> Catherine
>
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