[ensembl-dev] Question about annotation field(HGVSp)

Will McLaren wm2 at ebi.ac.uk
Mon Apr 27 09:34:26 BST 2015


Hello,

"%3D" is the URL-encoded version of the "=" character, so the unencoded
version reads NM_015658.3:c.1843C>T(p.=). The "p.="  means that the protein
sequence is unchanged.

We encode it this way since the "=" character is used elsewhere in the VEP
output as a delimiter, so its appearance in HGVSp strings would break
downstream parsers.

You can force VEP to print out "=" instead of "%3D" using --no_escape,
though of course you must then be careful parsing the results file!

Regards

Will McLaren
Ensembl Variation

On 27 April 2015 at 08:48, namchul ghim <chulghim at gmail.com> wrote:

> synonymous_variant         NM_015658.3:c.1843C>T(p.%3D)
>
> What does  the (p.%3D) means?
>
> Anybody help me !!!
>
>
>
>
>
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