[ensembl-dev] REST server 3.0 vep endopoint works only with human specie

mag mr6 at ebi.ac.uk
Tue Jul 22 17:36:00 BST 2014


Hi Paolo,

Thank you for reporting this and apologies for the error.

We were wrongly using some human-specific configuration for all species, 
this has now been fixed on the live server.

If you are using POST requests for VEP, please be aware that only human 
uses the vep cache.
For other species, we are still using direct database connection, which 
will result in lower performance.

If you are interested in getting faster POST support for other species, 
please contact us.


Regards,
Magali

On 22/07/2014 11:55, Paolo Cozzi wrote:
>
> Dear developer,
>
> I found an odd response from the vep/:species/region/ 
> <http://rest.ensembl.org/documentation/info/vep_region_post> of the 
> new ensembl REST server ( http://rest.ensembl.org/) while searching 
> for species other than human. For example, if I do 2 POST request with 
> curl on human and cow (the sample data are the same as in the VEP 
> webserver):
>
> $ curl -H "content-type:application/json" -H "accept:application/json" 
> --data '{ "variants" : ["1  909238 909238  G/C  +", "3  361464  
> 361464  A/-  +", "5  121187650 121188519  DUP"] }' 
> http://rest.ensembl.org/vep/human/region > output_human.txt
>
> $ curl -H "content-type:application/json" -H "accept:application/json" 
> --data '{ "variants" : ["1  909238 909238  G/C  +", "3  361464  
> 361464  A/-  +", "5  121187650 121188519  DUP"] }' 
> http://rest.ensembl.org/vep/cow/region > output_cow.txt
>
> I will find the same results (diff give me no output), even VEP gives 
> me 2 different results. Could be a problem of variation endpoint?
>
> Thanks for your support,
>
> best regards,
>
> Paolo.
>
>
>
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