[ensembl-dev] VEP dbNSFP plugin

Will McLaren wm2 at ebi.ac.uk
Fri Nov 15 09:57:21 GMT 2013


Thanks Michael, I've updated the plugin.

Will


On 14 November 2013 21:35, Michael Yourshaw <myourshaw at ucla.edu> wrote:

> I’m not sure this is the right list to bring this up, but the dbNSFP
> plugin can cause a problem on non-windows machines.
>
> The symptom is that if you select the ESP6500_EA_AF column option for
> this plugin, the Extra column in the VEP output will have a CR that might
> be interpreted as a line break immediately after the ESP6500_EA_AF value.
>
> This is because the dbNSFP data file has windows-style (CRLF) newlines
> and ESP6500_EA_AF is the last column in each record.
>
> An easy fix is to add a cleanup line in the dbNSFP plugin:
>     while(<TABIX>) {
> chomp;
> #remove trailing CR on linux platforms
> s/\r$//g;
> my @split = split /\t/;
>
> You might consider having VEP recode any forbidden semicolon, tab, CR, or
> LF (or other?) values that any plugin adds to EXTRA.
>
>
>>
> Michael Yourshaw
> UCLA Geffen School of Medicine
> Department of Human Genetics, Nelson Lab
> 695 Charles E Young Drive S
> Gonda 5554
>
> Los Angeles CA 90095-8348 USA
>
> myourshaw at ucla.edu
>
> 970.691.8299
>
> This message is intended only for the use of the addressee and may contain
> information that is PRIVILEGED and CONFIDENTIAL, and/or may contain
> ATTORNEY WORK PRODUCT. If you are not the intended recipient, you are
> hereby notified that any dissemination of this communication is strictly
> prohibited. If you have received this communication in error, please erase
> all copies of the message and its attachments and notify us immediately.
> Thank you.
>
>
>
>
>
> _______________________________________________
> Dev mailing list    Dev at ensembl.org
> Posting guidelines and subscribe/unsubscribe info:
> http://lists.ensembl.org/mailman/listinfo/dev
> Ensembl Blog: http://www.ensembl.info/
>
>
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://mail.ensembl.org/pipermail/dev_ensembl.org/attachments/20131115/1f128b88/attachment.html>


More information about the Dev mailing list