[ensembl-dev] Check if a gene has a pseudogene

Javier Herrero jherrero at ebi.ac.uk
Wed Aug 10 14:40:18 BST 2011


Hi Ryan

There is no direct link from a pseudogene to its parent known gene (assuming 
this exists, that is). Your best option is to align your pseudogenes of 
interest to all coding genes in that species.

I hope this helps

Javier

On Monday 08 Aug 2011 19:40:10 Ryan Giuliany wrote:
> Hi,
> 
> I think you're correct. To be more precise:
> 
> A gene either is or is not a pseudogene, but in the case where it *is* a
> pseudogene, in many cases the pseudogene was created via a gene
> duplication event of another, possibly protein coding, gene.  I suppose my
> questions would be better worded as "is there any way to check if a gene
> is a parent of a known pseudogene?".
> 
> Ryan
> ________________________________________
> From: carandraug at gmail.com [carandraug at gmail.com] On Behalf Of Carnë Draug
> [carandraug+dev at gmail.com] Sent: Monday, August 08, 2011 11:31 AM
> To: Ryan Giuliany
> Cc: dev at ensembl.org
> Subject: Re: [ensembl-dev] Check if a gene has a pseudogene
> 
> On 8 August 2011 19:06, Ryan Giuliany <rgiuliany at bccrc.ca> wrote:
> > Hi,
> > 
> > Is it possible to check if a gene has (not is) a known pseudogene?  I've
> > been sifting through the docs, and can't find anything.
> > 
> > Thanks!
> > Ryan
> 
> Hi Ryan
> 
> I believe a gene either is, or is not, a pseudo gene. Do you mean to
> ask if a gene has (or has not), a non-coding transcript?
> 
> Carnë
> 
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-- 
Javier Herrero, PhD
Ensembl Compara Project Leader
European Bioinformatics Institute (EMBL-EBI)
Wellcome Trust Genome Campus, Hinxton
Cambridge - CB10 1SD - UK




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