[ensembl-dev] Ensembl REST API | GET map/cdna/:id/:region

Ramiro Magno ramiro.magno at gmail.com
Wed Sep 11 18:04:50 BST 2019


Q7: What other values than "chromosome" are possible for the optional
parameters "coord_system" and "target_coord_system"?

On Tue, 10 Sep 2019 at 14:21, Ramiro Magno <ramiro.magno at gmail.com> wrote:

> Hi Devs,
>
> I have a few questions about the endpoint "map/cdna/:id/:region".
>
> Q1: How can I find what species work with this endpoint?
>
> Q2: Is there a way of specifying the "range" parameter so that it starts
> at 1 and goes till the end of the cDNA sequence? E.g., 1..end?
>
> Q3: In the doc, the description of the "id" parameter reads "An Ensembl
> stable ID". But only transcript ids are valid choices, correct?
> For example, making the nonsensical query with a gene id gives back a not
> so tidy error:
> https://rest.ensembl.org/map/cdna/ENSG00000115263/1..1000?content-type=application/json;include_original_region=1
> .
>
> Q4: What is the meaning of the variable "gap" in the json response? Is it
> gap=0 means exon, and gap=1 un-mappable region? When I exceed the end
> position of the transcript in the "range" parameter I always get the excess
> as a region flagged as gap=1.
>
> Q5: When I get an excess region as a result of asking a cDNA sequence that
> goes beyond the length of transcript, why are the genomic coordinates
> "start" and "end" reported as if they were in cdna coordinate system? E.g.,
> the request:
> https://rest.ensembl.org/map/cdna/ENST00000375497/1..1000?content-type=application/json;include_original_region=1 yields
> a last block whose coordinates are start=800, end=1000 for both coordinate
> systems: "cdna" and "chromosome". Would it not make more sense to just
> report NA or Null instead?
>
> Q6: What is the meaning of the "rank" variable in the json output?
>
> Many thanks in advance!
>
> Cheers, Ramiro
>
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