[ensembl-dev] GRCh37 - homo_sapiens is not a valid species name (check DB and API version)

Rares Vernica rvernica at gmail.com
Mon Oct 29 04:07:41 GMT 2018


Hello,

I'm having trouble with the public database when using the GRCh37 assembly.
This is what I run:

> ./vep --cache --refseq --assembly GRCh37 --fasta
~/.vep/homo_sapiens/94_GRCh37/Homo_sapiens.GRCh37.75.dna.primary_assembly.fa.gz
--input_file 1.tsv --port 3337

-------------------- WARNING ----------------------
MSG: homo_sapiens is not a valid species name (check DB and API version)
FILE: Bio/EnsEMBL/Registry.pm LINE: 1334
CALLED BY: Bio/EnsEMBL/Registry.pm  LINE: 1109
Date (localtime)    = Mon Oct 29 03:49:22 2018
Ensembl API version = 94
---------------------------------------------------

-------------------- EXCEPTION --------------------
MSG: Can not find internal name for species 'homo_sapiens'
STACK Bio::EnsEMBL::Registry::get_adaptor
/usr/local/src/ensembl-vep/Bio/EnsEMBL/Registry.pm:1111
STACK Bio::EnsEMBL::VEP::BaseVEP::get_adaptor
/usr/local/src/ensembl-vep/modules/Bio/EnsEMBL/VEP/BaseVEP.pm:307
STACK Bio::EnsEMBL::VEP::BaseVEP::get_database_assembly
/usr/local/src/ensembl-vep/modules/Bio/EnsEMBL/VEP/BaseVEP.pm:419
STACK Bio::EnsEMBL::VEP::BaseRunner::setup_db_connection
/usr/local/src/ensembl-vep/modules/Bio/EnsEMBL/VEP/BaseRunner.pm:123
STACK Bio::EnsEMBL::VEP::Runner::init
/usr/local/src/ensembl-vep/modules/Bio/EnsEMBL/VEP/Runner.pm:118
STACK Bio::EnsEMBL::VEP::Runner::run
/usr/local/src/ensembl-vep/modules/Bio/EnsEMBL/VEP/Runner.pm:194
STACK toplevel ./vep:224
Date (localtime)    = Mon Oct 29 03:49:22 2018
Ensembl API version = 94
---------------------------------------------------

It works with --online but I would like to use the *Variant identifiers*
<https://uswest.ensembl.org/info/docs/tools/vep/vep_formats.html#id> input
format and that does not work with --offline.

Any ideas what I'm doing wrong?

Thanks!
Rares
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