[ensembl-dev] REST - map endpoint

Daniel Suveges ds26 at sanger.ac.uk
Fri Jun 16 13:16:31 BST 2017


Hi Guys,


I’m trying to use the map endpoint of the REST service (to map between the human GRCh37 and 38 build) and I’m encountering some unexpected behavior:

Let’s take the variant rs11553699 for example:
it’s GRCh37 coordinates: 12:122216910
it’s GRCh38 coordinates: 12:121779004

If I want to map it’s GRCh37 coordinates to the newer build it works:
http://rest.ensembl.org/map/human/GRCh37/12:122216910..122216910:1/GRCh38?content-type=application/json

But when I’m trying to do the same in the opposite direction, the ‘mappings’ array is empty in the returned json:
http://rest.ensembl.org/map/human/GRCh38/12:121779004..121779004:1/GRCh37?content-type=application/json

For other GRCh38 coordinates mapping works, this position has coordinates in both build, so it is not clear to me why the second query seemingly fails.
Thank you very much for your help!

Best,
Daniel
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