[ensembl-dev] New VEP Plugin (PON_P2)

[Abhishek Niroula]

Dear all,

I would like to share a VEP Plugin f(PON_P2) for obtaining predictions from
PON-P2.

PON-P2 is a machine learning-based tool for predicting pathogenicity of
amino acid substitutions in human proteins. The method computes reliability
score for each variant and classifies them into three groups (Pathogenic,
Neutral and Unknown) based on the predicted score and the reliability. The
article describing PON-P2 is published in PLoS One (
http://www.ncbi.nlm.nih.gov/pubmed/25647319). The tool is available at
http://structure.bmc.lu.se/PON-P2/. <http://structure.bmc.lu.se/PON-P2>

The plugin and a supporting python script required to connect to PON-P2
server is attached with this email. You can also find the scripts and more
information about the plugin at http://structure.bmc.lu.se/PON-P2/vep.html/.


Best Regards
Abhishek Niroula
Department of Experimental Medical Science
Faculty of Medicine, Lund University
Lund, Sweden
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