[ensembl-dev] SIFT score differences.

[binit treesa]

Hi team,

Recently we found a source dbNSFP which is similar to VEP result.

Usually we run VEP with variants to get the SIFT and polyphen score and its
prediction.
While comparing these two files, I noted that there is slight difference in
the sift and polyphen score but the prediction remains same:

The version we compared :
dbNSFP  : it support ensembl v66
VEP result  : VEP tool v75 (ensembl v75)

It will be good if you can point out the reasons behind this score
differences.
Also please share the procedure to calculate the SIFT and Polyphen.

Thanks,
Treesa Binit
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