[ensembl-dev] Proteins
Leila Alieh
alieh.leila at gmail.com
Sat Jun 13 00:15:53 BST 2015
Hi!
I have a list of Ensembl protein IDs and I want to know wich protein are
they referring to, specifically I want to know the difference between
different proteins derived from the same gene. Is there an annotated
description linked to these Ensembl protein ID which can give me this
information? Or should I retrieve the protein sequence and blast them
against each other to see in what they differ? If the difference is small
and I don't find a domain associated to them how can I know that the
affected aa are not relevant for the function of the protein
(phosphorilated residues or key aa for the proper folding of the protein)?
I searched a bit in internet but I couldn't find a straightforward way to
do it (if I query biomart I have the same description for the gene, didn't
I select the right attributes?)
Also I used perl ENSEMBL API to find the domain IDs associated to some
exons of interest. Is there any database in which I can search the meaning
of these protein IDs? they are from different databases (PFAM, Interpro,
etc), should I look to each database separately?
Thanks!
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