[ensembl-dev] missing transcript

[Nathalie Conte]

Hello, Could I have some help on this?
Thanks
Nathalie

On 24 Jul 2014, at 15:31, Nathalie Conte <nconte at ebi.ac.uk> wrote:

> Hi Dev team,
> 
> In Ensembl, there is only one protein coding transcript for Fign gene: ENSMUST00000131615
> 
> http://www.ensembl.org/Mus_musculus/Transcript/Summary?db=core;g=ENSMUSG00000075324;r=2:63971507-64098038;t=ENSMUST00000131615
> 
> The ATG is here in exon-2.
> 
>  However, historically there has been a second protein coding annotated in Ensembl, ENSMUST00000166144, which has been removed at some point. For this second transcript the ATG starts in the last exon (in frame and 33 bp downstream of the ATG in exon-2)
> 
> http://may2012.archive.ensembl.org/Mus_musculus/Transcript/Summary?db=core;g=ENSMUSG00000075324;r=2:63809564-63936095;t=ENSMUST00000166144
> 
> There seems to have biological evidence that this second transcript exist and it would be therefore very useful to understand as to why this transcript has been removed and is not considered protein coding by Ensembl any more.
> 
> Thanks for any info,
> 
> Nathalie
> 

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