[ensembl-dev] VEP Grantham amino acid distance

[cj5 at sanger.ac.uk]

Hi Guillermo,
Not sure of your requrements, but if you want a simple lookup of a mtrix based upon the original paper,

Grantham, R. Amino Acid Difference Formula to Help Explain Protein Evolution, Science 1974 Sep 6;185(4154):862-4.

please see attached.

regards
Chris Joyce

> Hello,
>
> I'm trying to calculate Grantham AA distance as a VEP plugin.
>
> Currently I'm doing it parsing HGSVp and calculating distance between
> the two AA being parsed.
>
> Do you guys believe there's an easier and more efficient way to do this?
>
> Thank you.
>
> Best regards,
> Guillermo.
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