[ensembl-dev] Huge branch lengths in gene trees
Sébastien Moretti
sebastien.moretti at unil.ch
Wed Oct 17 07:46:16 BST 2012
Thanks Javier
I can skip my analyses on these branches for now.
Sébastien
> Dear Sébastien
>
> Indeed, that is an upper branch length limit set by TreeBeST. This
> family is especially difficult to resolve as it contains essentially 3
> types of genes: full length, N-terminal part only or C-terminal part
> only. As such, many pairs of genes do not overlap at all in the
> alignment. As you can imagine, it is very difficult for the phylogenetic
> reconstruction algorithm to address these families.
>
> We are working on a couple of developments that might help in those
> situations. We will let you know more if we make any progress.
>
> Javier
>
>
> On 16/10/12 15:29, Moretti Sébastien wrote:
>> Hi
>>
>> I found some gene trees that have huge branch lengths:
>> e.g. tree ENSGT00560000076605, gene ENSCJAG00000001973
>> The branch leading to that gene/leaf is 100000 long.
>> http://www.ensembl.org/Callithrix_jacchus/Gene/Compara_Tree?g=ENSCJAG00000001973;r=ACFV01174532.1:4628-45447;t=ENSCJAT00000003772
>>
>>
>> What does it mean ?
>> Is it an upper branch length limit ?
>>
>> Thanks
--
Sébastien Moretti
SIB Vital-IT EMBnet, Quartier Sorge - Genopode
CH-1015 Lausanne, Switzerland
Tel.: +41 (21) 692 4079/4221
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