[ensembl-dev] a question about nonsense_mediated_decay in Homo_sapiens

李雪楠 lixuenan2010 at hotmail.com
Tue Apr 19 03:51:01 BST 2011


I am a student in bioinformatics who is eager to know where is your data about  nonsense_mediated_decay in Homo_sapiens from, automatically annotation or experiment data ?as the definition of NMD is that If the coding sequence (following the appropriate reference) of a transcript finishes >50bp from a downstream splice site then it is tagged as NMD. If the variant does not cover the full reference coding sequence then it is annotated as NMD if NMD is unavoidable i.e. no matter what the exon structure of the missing portion is the transcript will be subject to NMD. 
so i design perl programs to find the NMD. for example ENST00000511104,ENST00000393966 ENST00000433422 these data's transcript type in your website are different from my perl programs result  so i need your help to work out my confusing,   thanks a lot.  		 	   		  
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