[ensembl-dev] Genes with identical symbols but different ENSG

[Duarte Molha]

Anyone can answer this? Thanks

On Tue, 19 Mar 2019, 14:13 Duarte Molha, <duartemolha at gmail.com> wrote:

> Dear Devs
>
> Could you help me understand why the gene
>
> ATXN7
>
> Has 2 ENSG ids. but they both map to the same external Reference:
> ATAXIN 7; ATXN7 [*607640] (MIM gene record; description: ATAXIN 7; ATXN7,)
>
>
> The Gene with the most transcripts associated with it is:
> ATXN7 (Human Gene)
> ENSG00000163635 3:63898399-64003453:1
>
> But Overlapping with it you have
> ATXN7 (Human Gene)
> ENSG00000285258 3:63864557-64003462:1
>
> Would it not make sense to add all transcript to the 1st ID and drop the
> second?
> This unfortunately is not the only gene where this occurs
>
> For example the HGNC symbol DIABLO is associated with 2 ENSG IDs (also
> overlaping
> The same with CCDC39, IGF2, MATR3, PDE11A, RMRP, SCO2, SPATA13 and TBCE
>
> I am sure this is not the only ones where this is true and it creates a
> bit of a problem because now I need to be merging distinct entities or
> choose between one of the 2 entries as the main entry for that gene symbol.
>
> Your help on why this occurs and any possible solutions as to how to only
> select the main one would me much appreciated
>
> Best regards
>
> Duarte Molha
>
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