[ensembl-dev] Transcript Biotype

[Wolf Beat]

Hi,


i'm trying to solve an issue where a (for us) important lncRNA changed biotype in ensembl since the oct 2018 release.

The gene in question, GATA6-AS1, can be found here:

https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000266010;r=18:22164886-22169878


Here its stated that all its Transcripts are antisense.


But in the archive:


http://jul2018.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000266010;r=18:22166898-22168968


Its a lncRNA.


Now if i read the description of Antisense, that seems technically true. But lncRNA as a biotype seems much more precise.


The only explanation i can find is that because of: GATA6-AS-208, which is new and actually does overlap GATA6-201, all transcripts of GATA6-AS1 lost their lncRNA status and became antisense.

Does that mean that in ensembl it is not possible to have lncRNAs that overlap other genes? To me that sounds like a bug, but i might just misunderstand the biotypes.


Thank you for your clarifications


Beat Wolf