[ensembl-dev] efficient way to calculate high-LD pairs to a single variant with API?

[andrew126 at mac.com]

Hi,

Using the API's LDFeatureContainer and LDFeatureContainerAdapter r^2 values seem to be calculated between all variant pairs.  Is there a way to avoid all unnecessary calculations if I am only interested in high-LD pairs to a single SNP across a region/slice?  So I only need (n-1) r^2 calculations across a region, and not n*(n-1) r^2 calculations.

Thanks for any guidance.

Best,

Andrew