[ensembl-dev] Question regarding gene Annotations discrepancies between GRCh38 and 37 on the latest API.

Duarte Molha duartemolha at gmail.com
Wed Jul 1 11:03:03 BST 2015

Dear developers

It was my understanding that ensembl would be keeping 2 databases running
in parallel for both GRCh38 and GRCh37 and so all genes would be receiving
annotation updates and both databases could be queried with the latest and
greatest ensembl perl api.

However I am finding inconsistencies in gene annotation what have left me

Take for example gene DNAAF5


If you query ensembl GRCh38 V80, the gene is there properly annotated


However, on GRCh37 V80, the gene is still annotated with the previous HGNC
symbol HEATR2


the ENSEMBL gene ID is the same in both cases :


Is my thinking flawed? What is the reason for the out-of-date gene
annotation for this gene?

Many thanks

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