[ensembl-dev] Ensembl IDs versus HGNC

Genomeo Dev genomeodev at gmail.com
Thu Feb 20 11:43:11 GMT 2014


Hi,

I have a set of ~ 6000 Ensembl IDs which I want to map to HGNC IDs. I am
faced with the following situation:

Based on Ensembl Biomart or Ensembl Rest, there are ~ 4000 of these that
have HGNC IDs.

Based on HGNC biomart, there are ~ 3000 which have HGNC IDs. HGNC DB
mention that themselves use mapping supplied by Ensembl.

The IDs mapped from each of these sources are not always the same.

Questions:

- What is causing the different level of coverage?
- What is causing the differences in specific mapping if all of it is done
by Esembl?
- How often does this mapping change at any of these sources?
- How do other sources like NCBI assign Ensembl IDs to their Entrez IDs?
- What is the best way of getting HGNC IDs for Ensembl IDs? from Ensembl or
HGNC DB?

Thanks!

-- 
G.
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