[ensembl-dev] RNA Edits

PATERSON Trevor trevor.paterson at roslin.ed.ac.uk
Thu Mar 22 17:54:21 GMT 2012


Hi

Is there any documentation to help me understand what is going on with the 'RNA Edits' that are cached on construction of a SequenceAdaptor in the PerlAPI?

The only doumentation that I can find  about RNA Edits is in an apparently out of date file on the ftp server...
ftp://ftp.ensembl.org/pub/ensembl/misc-scripts/attribute_types/attrib_type.txt
which cryptically says for this attribute type:

# Drosophila. Sometimes sequences have been manually altered to remove one base, and this alters the whole translation
145     _rna_edit       rna_edit        RNA edit


Is there better documentation on the various attribute types somewhere?

Also

How are RNA Edits related to LRGs? ( are they LRGs? in humans they are on the same coordinate system...)

Under what circumstances are sequences retrieved by the SequenceAdaptor 'RNA Editted' according to the cached information?

I am guessing that the RNA Edits are just an edge-case that have been levered in to the schema, I only became aware of them when I started looking into using LRGs.

Thanks

trevor



Trevor Paterson PhD
trevor.paterson at roslin.ed.ac.uk<mailto:trevor.paterson at roslin.ed.ac.uk>

Bioinformatics
The Roslin Institute
Royal (Dick) School of Veterinary Studies
University of Edinburgh
Easter Bush
Midlothian
EH25 9RG
Scotland UK

phone +44 (0)131 651 9157

http://bioinformatics.roslin.ed.ac.uk/

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