[ensembl-dev] precedence of snp consequences

Andrea Edwards edwardsa at cs.man.ac.uk
Sun Jan 23 20:01:41 GMT 2011


Hello

What are the rules that ensembl uses to determine the 
display_consequence of a SNP from all of its possible consequences?

As an example I am looking at a SNP whose main consequence 
(display_consequence) = 3PRIME_UTR and all consequences 
(consequence_type) are given as NMD_TRANSCRIPT, 3PRIME_UTR

Is there a list or ranking you use for consequences to say that 
3PRIME_UTR is more important than NMD_TRANSCRIPT?

Will the main consequence always be last in the list of the 
consequence_type property?

One reason I ask is because I am trying to apply the same consequence 
ranking to the results returned by the snp_effect_predictor script. That 
script returns one row/line for every consequence in the 
consequence_type field and the order of the consequences in the rows 
returns seems to be the same as the order of the consequences in the 
consequence_type property. If the display_consequence is always last in 
the list then i can assume the last row returned for a transcript 
variant is the 'main consequence'

thanks




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